Red blood cell (RBC) suspensions in confined microflows: Pressure-flow relationship
نویسندگان
چکیده
منابع مشابه
Pressure-driven occlusive flow of a confined red blood cell.
When red blood cells (RBCs) move through narrow capillaries in the microcirculation, they deform as they flow. In pathophysiological processes such as sickle cell disease and malaria, RBC motion and flow are severely restricted. To understand this threshold of occlusion, we use a combination of experiment and theory to study the motion of a single swollen RBC through a narrow glass capillary of...
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The general problem of microrheology is to predict the macroscopic flow properties of a material from a detailed description of the behavior of its constituent elements. This approach has been used to study suspensions of human red cells in plasma or Ringer's solution flowing steadily in rigid tubes 8-25 times the red cell diameter by observing individual cell motions under the microscope. The ...
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We analyze the migration characteristics of a droplet in an oscillatory flow field in a parallel plate microconfinement. Using phase field formalism, we capture the dynamical evolution of the droplet over a wide range of the frequency of the imposed oscillation in the flow field, drop size relative to the channel gap, and the capillary number. The latter two factors imply the contribution of dr...
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The modeling of blood flows confined in micro-channels or micro-capillary beds depends on the interactions between the cell-phase, plasma and the complex geometry of the network. In the case of capillaries or channels having a high aspect ratio (their longitudinal size is much larger than their transverse one), this modeling is much simplified from the use of a continuous description of fluid v...
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BACKGROUND Almost 2 percent of murine blood red blood cells (RBCs) are destroyed each day and are replaced by fresh RBCs generated through the process of erythropoiesis. RBCs to be destroyed are phagocytosed by macrophages in the reticuloendothelial system, especially in the spleen. CD47 molecules on RBCs may regulate the susceptibility of RBC to destruction by phagocytosis because its recognit...
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ژورنال
عنوان ژورنال: Medical Engineering & Physics
سال: 2017
ISSN: 1350-4533
DOI: 10.1016/j.medengphy.2017.08.006